The Detroit Lions should win their matchup against the Green Bay Packers at 4:25 p.m. ET on Sunday, Sept. 7, based on our computer projections. If you're seeking additional projections on the final score, spread, and point total, we've got you covered below.
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Packers vs. Lions Game Info and TV Channel
- When: Sunday, September 7, 2025 at 4:25 p.m. ET
- Where: Lambeau Field in Green Bay, Wisconsin
- TV: CBS
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- Live Stream: Watch this game on Paramount+ (Regional restrictions may apply)
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Listen to the game on 97.3 The Game
Packers vs. Lions Odds and Betting Info
- Spread favorite: Packers (-2.5)
- Moneyline: Packers (-134), Lions (+113)
- Total: 47.5 points
Packers vs. Lions Prediction
- Pick ATS: Lions (+2.5)
- Pick OU: Over (47.5)
Prediction:
Lions 27 - Packers 24
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Packers vs. Lions Betting Insights (2024 Stats)
- The Packers went 9-8-0 ATS last season.
- The Lions won 12 games against the spread last season, while failing to cover five times.
- When playing as at least 2.5-point favorites last season, Green Bay had an ATS record of 6-5.
- The Packers and their opponents combined to go over the point total eight out of 17 times last season.
- The Lions and their opponent combined to go over the point total nine out of 17 times last season.
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